dept of biochemistry and molecular biophysics



 

BIO 5318 - DNA Repair

Handouts

 

 Date

 Topic

 Lecturer

1

 Jan 24

 Overview of DNA Repair Pathways; DNA damage response; Epistasis analysis

 Burgers

2

 Jan 31

 ss and ds DNA stability, DNA breaks, DNA damage chemistry, Xenobiotics, Oxidative damage

 Taylor

3

 Feb 7

 DNA photochemistry, Photoreactivation

 Taylor

4

 Feb 14

 DNA polymerases, fidelity, and nucleotide insertion opposite damage

 Taylor

5

 Feb 21

 Mismatch repair; Damage reversal chemistry

 Burgers

6

 Feb 28

 Postreplication repair, Fork regression and restart

 Burgers

7

 Mar 7

 Recombinational DNA Repair

 Powell

8

 Mar 14

 Double strand break repair, NHEJ

 Powell

9

 Mar 21

 Cell cycle control of DNA repair; checkpoint, p53

 Powell

10

 Mar 28

 Nucleotide excision repair, UvrABC

 Ellenberger

11

 Apr 4

  Base excision repair

 Ellenberger

12

 Apr 11

 Nucleotide excision repair, Xeroderma, transcriptional coupling, Crosslink repair

 Ellenberger

13

 Apr 18

 Damage induced and programmed mutagenesis, immune system

 Burgers


PDF files can be viewed with the free Adobe Acrobat Reader.