dept of biochemistry and molecular biophysics




Faculty

picture of roberto galletto
Roberto Galletto
 Assistant Professor
Dept. of Biochemistry and
Molecular Biophysics

Office: 252 McDonnell Science Building
Phone: 314-362-4368
Fax: 314-362-7183
Email: galletto@biochem.wustl.edu

Lab Website
Research Opportunities

Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110



Research Interests

Mechanistic studies of DNA motor proteins.



Selected Publications


  • Galletto, R. and Kowalczykowski, S.C. RecA. Curr Biol 17:R395-397 (2007).

  • Galletto, R., Amitani, I., Baskin, R.J., Kowalczykowski, S.C. Direct observation of individual RecA filaments assembling on single DNA molecules. Nature 443:875-878 (2006).

  • Galletto, R., Jezewska, M.J., Bujalowski, W. Kinetic mechanism of rat polymerase ß - dsDNA interactions. Fluorescence stopped-flow analysis of the cooperative ligand binding to a two-site one-dimensional lattice. Biochemistry 44:1251-1267 (2005).

  • Galletto, R., Jezewska, M.J., Maillard, R., Bujalowski, W. The nucleotide-binding site of the Escherichia coli DnaC protein. Molecular topography of DnaC protein - nucleotide cofactor complexes. Cell Biochemistry and Biophysics 43:331-354 (2005).

  • Galletto, R., Jezewska, M.J., Bujalowski, W. Kinetics of allosteric conformational transition of a macromolecule prior to ligand binding. Analysis of stopped-flow kinetic experiments. Cell Biochemistry and Biophysics 42:121-144 (2005)

  • Jezewska, M.J., Galletto, R., Bujalowski, W. Interactions of the RepA helicase hexamer of plasmid RSF1010 with the ssDNA. Quantitative analysis of stoichiometries, intrinsic affinities, cooperativities, and heterogeneity of the total ssDNA-binding site. Journal of Molecular Biology 343:115-136 (2004).

 

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