Faculty

Timothy M. Lohman
Brennecke Professor of Biological Chemistry
Dept. of Biochemistry and
Molecular Biophysics

Office: 2801 North Building
Phone: 314-362-4393
Fax: 314-362-7183
Email: lohman@biochem.wustl.edu

Lab Website
Research Opportunities

Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110

Shereda, R.D., Kozlov, A.G., Lohman, T.M., Cox, M.M. and Keck, J.L. SSB as an organizer/mobilizer of genome maintenance complexes. CRC Critical Reviews in Biochemistry and Molecular Biology 43:289-318 (2008).
Wu, C.G. and Lohman, T.M. Influence of DNA end structure on the mechanism of initiation of DNA unwinding by the Escherichia coli RedBCD and RecBC helicases. J Mol Biol 382:312-326 (2008).
Lohman, T.M., Tomko, E.J. and Wu, C.G. Non-hexameric DNA helicases and translocases: Mechanisms and regulation. Nat Rev Mol Cell Biol. 9:391-401 (2008).
Wong, C.J. and Lohman, T.M. Kinetic control of Mg(2+)-dependent melting of duplex DNA ends by Escherichia coli RecBC. J Mol Biol. 378:759-775 (2008).
Niedziela-Majka, A., Chesnik, M.A., Tomko, E.J. and Lohman, T.M. B\. Stearothermophilus PCRA monomer is a single stranded DNA translocase but not a processive helicase in vitro. J Biol Chem 282:27076-27085 (2007)
Tomko, E.J., Fischer, C.J., Niedziela-Majka, A. and Lohman, T.M. A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA. Mol Cell 26:335-347 (2007).
Roy, R., Kozlov, A.G., Lohman, T.M. and Ha, T. Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein. J Mol Biol 369:1244-1257 (2007).